Two people went to the hospital at about 3:20 a.m. Monday with serious injuries after their pickup truck crashed into a tree after veering of the roadway while traveling northbound lanes in the 600 block of North Main Street.The passenger had to be extricated by firefighters from the crushed cab of the vehicle, according to Manteca Police Sgt. Michael Aguilar. Both the 28-year-old female driver and the 50-year-old passenger were transported to the San Joaquin County General Hospital trauma center by ambulance following the crash, Aguilar said. Police could not identify the driver due to the seriousness of her injuries as the family had not yet been notified.The MAIT, major accident investigation team, was called to the scene to handle the investigation into the crash.